Although worms can normally sense undiluted octanol equally well on and off food, mutant worms with ASH neurons removed by laser microsurgery fail to respond to undiluted octanol on food.

This basal lifespan extension was dependent on DAF-16, as it did not occur when ASI neurons were ablated in daf-16 mutant worms. Importantly, ablation of the ASI neurons in daf-16 mutants did ...

Too much acetylcholine leads to the excitatory imbalance that causes the seizure-like behavior in the mutant worms. When more ...