the axon - the long part of the motor neuron cell that connects to the muscle - was shorter than in healthy cells. And the movement of the mitochondria, which travel up and down the axons ...
the team discovered that they could restore the autophagy that was lost and regain some of the neuron function that was impaired due to axonal mitochondria loss. This not only shows that depletion ...
Prof. Azem explains, "The disease we studied is caused by a mutation in a protein called TIMM50, which plays a crucial role in importing other proteins into the mitochondria—the organelle ...