Methotrexate is a cornerstone of therapy worldwide for juvenile idiopathic arthritis, yet there remains vast variability in drug dosing and administration, as well as unpredictable outcomes on the ...

Daily oral treatment with T-614, a member of the methanesulfonanilide family of cyclo-oxygenase 2 inhibitors, might be an alternative to weekly methotrexate therapy for rheumatoid arthritis (RA).

Methotrexate sodium 2.5mg ... Pregnancy: exclude status prior to initiation. Nursing mothers: not recommended (during and for 1 week after the last dose).

Methotrexate (MTX) remains a cornerstone in the treatment of rheumatoid arthritis, despite the advent of newer biologic therapies, because of its long-term efficacy and safety. However ...