DCs occur in different manifestations: interdigitating cells, follicular dendritic cells, lymphoid dendritic cells, many of them with subsets defined according to anatomical site, maturation or ...
Common diseases susceptible to immunotherapy without standard curative protocols—such as multiple myeloma and low-grade non-Hodgkin lymphoma — should be investigated early 44. Dendritic cells ...
Dendritic cells regulate both innate and adaptive immune ... and immune response (reviewed in reference 5). Tissue and lymphoid DCs reside in an inactive, highly phagocytic state at sites of ...
Dark zone lymphoma includes aggressive B-cell lymphomas with shared molecular features. While some respond to escalated ...
Multiple sclerosis (MS) is considered to be a predominantly T-cell-mediated disease, and emerging evidence indicates that dendritic cells have a critical role in the initiation and progression of ...
Plasmacytoid dendritic cells (pDC) primarily function as weak antigen-presenting cells (APC), but have also been shown to ...
Whereas dendritic cells are critical for kickstarting the cancer immunity cycle in the lymph node, both dendritic cells and monocytes are needed to fully activate T cells in the tumor. The ...
Lymphatic system is composed of treelike lymphatic vessel networks, lymph nodes and associated migratory immune cells ... conditions via controlled expansion of lymphatic capillary networks and ...
CMN-005 is under clinical development by Benecyte and currently in Phase II for Mantle Cell Lymphoma. According to GlobalData, Phase II drugs for Mantle Cell Lymphoma have a 31% phase transition ...