Penn Engineers have modified lipid nanoparticles (LNPs) -; the revolutionary technology behind the COVID-19 mRNA vaccines -; to not only cross the blood-brain barrier (BBB) but also to target specific ...
Engineers have developed a lipid nanoparticle (LNP) that delivers mRNA therapeutic to the placenta to treat pre-eclampsia in mice with human trials on the horizon.
This paper presents the important discovery that lipid metabolic imbalance caused by Snail, an EMT-related transcription factor, contributes to the acquisition of chemoresistance in cancer cells.