DCs中的STING激活促进IFN-β分泌，激活CD8+ T和NK细胞，释放IFN-γ和GzmB进行肿瘤杀伤。所有这些因素最终放大了抗肿瘤治疗效果。view more 结合DNA损伤剂和 ...

STING activation in DCs promotes IFN-β secretion to activate CD8+ T and NK cells, which release IFN-γ and GzmB for tumor killing. All these factors eventually amplify the antitumour therapeutic ...

Published this week in Cell Reports Medicine, the study reveals that the drug lurbinectedin, an approved second-line therapy for SCLC, activates the STING-IFN signaling pathway to enhance the ...