All 123 patients had a flare of OA at baseline, according to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and received celecoxib 200 mg once daily for 7 days.
randomly received celecoxib 200 mg/day or rofecoxib 25 mg/day for three weeks. After a one-week washout period, the patients were crossed over to treatment with the opposite COX-2 inhibitor for ...
The study group received a single 400 mg dose of celecoxib, one hour before surgery, and 200 mg of celecoxib every 12 hours for five days, along with patient-controlled analgesic (PCA) morphine.