Initially, T cell engineering depended on lentiviral or retroviral vectors to deliver DNA fragments into a cell for homologous recombination ... directed repair mechanisms, CRISPR editing can ...
The CRISPR molecular scissors have the potential to revolutionize the treatment ... Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements. Commun Biol.
The precise insertion of DNA sequences using the homology-directed repair (HDR) pathway is one potential use of the CRISPR/Cas genome editing technology. Various circumstances could influence the ...