A high anion gap metabolic acidosis means the pH is low and the blood is not electrically neutral. A normal anion gap ...

Indeed, phenformin, an antidiabetic drug that belongs to the same class as metformin, was withdrawn from the market in 1977 because of the high incidence of lactic acidosis associated with its use.

[6,7,8,9,10,11] Published reports that evaluated topiramate-associated hyperchloremic, normal anion-gap, metabolic acidosis were identified via a MEDLINE search (1966-May 2007) and included six ...

Use of the Naranjo et al. [12] adverse drug reaction probability scale indicated a probable relationship between hyperchloremic, normal anion-gap, metabolic acidosis and topiramate. This adverse ...