Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for ...

We use live-cell imaging to track the behavior of epithelial sheets of keratinocytes in response to transforming growth factor β (TGFβ), which stimulates collective ... This usually arises either from ...

Transforming growth factor-beta (TGF-β), a well-known ... of Sciences revealed the molecular mechanism of TGF-β signaling ...

We know today that Wnt and a handful of other signalling systems (Notch, Hedgehog, TGFβ (transforming growth factor-β)–BMP ... activate surface receptors, signal transduction components ...

Second, key pathway components suspected of participating ... There is increasing evidence regarding the existence of growth factor signaling pathways that impact different RNA processing events ...

Cordycepin, derived from fungi, shows promise in cancer therapy by inhibiting growth factor signaling pathways critical for ...

The signaling pathway, which is mediated by the protein GP130, plays a central role in cell communication and influences the activity of the transcription factor ... tumor growth can be slowed ...

This two-pronged attack hits an essential signaling pathway that drives many breast cancers that are more resistant to ...

PEG-MGF, or polyethylene glycol-modified mechanogrowth factor, is a peptide that has garnered attention in scientific ...

Campus Chemical Instrument Center, Mass Spectrometry & Proteomics Facility, The Ohio State University, Columbus, USA ...

Diabetes drug development gets an advance in study that shows Inceptor binds excess insulin within the beta cell and directs it towards degradation.

Thus, in HR + /HER2 + breast tumors a vicious cycle is established between ER genomic and non-genomic mechanisms of action and the growth ... pathway). Membrane associated ER binds to GF signaling ...