The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...
CXCR4-CCR7 Heterodimerization Is a Driver of Breast Cancer Progression. Life, Vol. 11, Issue. 10, p. 1049. Provides a comprehensive overview of recent discoveries and current understandings of G ...
Septerna (Nasdaq: SEPN), a biotechnology company discovering and advancing novel, oral small molecule medicines targeting G protein-coupled receptors (GPCRs), visits the Nasdaq MarketSite in Times ...
A number of cell surface and nuclear receptors mediate their actions via dimerization. While this has been well established, the dimerization of G-protein coupled receptors (GPCRs) (that ...
G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...
A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists ...
Receptors are cellular components that trigger internal changes based on external signals. Researchers have built a new synthetic receptor with incredibly broad potential to program cell activity, ...
Kokumi refers to the enhanced and more delicious state of food flavor. However, the underlying neuroscientific mechanisms remain largely unexplored. Our previous research demonstrated that ornithine ...
A cell’s ability to react to its surroundings is one of its fundamental roles. Therefore, it makes sense that one of the ...