Applying topical treatments, including medicated creams and ointments, directly to the fissure can help relieve anal fissure ...
Botulinum toxin A appears to be a safe and effective short-term treatment of chronic anal fissure, demonstrating a healing rate of 70-98% after two to four months. Botulinum toxin A has been shown ...
CONCLUSION: Although early recurrence can occur, topical GTN ointment is effective in healing chronic anal fissures in children.