When a DSB happens in DNA, it's like a load-bearing beam in a building breaking. A careful ... More information: Youngkyu ...

Scientists have mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

Genetic recombination is a complex process that involves alignment of two homologous DNA strands, precise breakage of each strand, equal exchange of DNA segments between the two strands ...

To accomplish this, each strand of existing DNA acts as ... As the helicase moves along the DNA molecule, it continues breaking these hydrogen bonds and separating the two polynucleotide chains ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, ...

Nitroimidazole derivatives act by causing DNA damage, with loss of the helical structure, impaired template function and strand breakage. Metronidazole is commonly given as 2 g single dose on ...

The two strands of the DNA helix are unzipped by breaking of the weak Hydrogen bonds ... RNA polymerase moves along the DNA strand. Free RNA nucleotides form hydrogen bonds with the exposed ...

resulting in DNA damage in the form of loss of helical structure, impaired template function, and strand breakage, which eventually leads to cell death. Tinidazole was approved by the FDA in May ...