During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...
During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...
Tumours often exhibit replication stress as a consequence ... the toxicity of DNA-damaging drugs can be reduced by the activities of several DNA repair pathways that remove lesions before they ...
DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of DNA DNA replication is the process by which a cell makes an identical ...
If you've looked at the activity (or even the text version of the activity), you know how a section of DNA instructs a cell how to make a protein. Actually, that's DNA's main purpose: to make ...
DNA replication, repair, and damage response, collectively called the 3Rs, support genome stability and faithful genetic inheritance. Proteins involved in the 3Rs are genome guardians that prevent a ...
In previous work, using the reconstituted DNA replication system, we have identified the molecular functions for the effector kinase, Rad53, in controlling fork progression and origin activation by ...