Considering their ubiquity, it seems safe to predict that ion channel mutations will be found to be involved in many diseases. The evolution of the lipid cell membrane solved one problem and ...

Ion channel proteins are found on all cell types and allow the passage of ... ther-mophila, which is geared toward membrane protein expression, and its post-translational machinery, which supports ...

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell ...

Our laboratory uses a combination of structural biology and biophysical techniques to discover how ion channels and membrane-embedded enzymes function at the atomic level. The proteins we study are ...

Discover how Nobel laureate Ardem Patapoutian's research on PIEZO channels revolutionizes our understanding of human biology.

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their ...

LMU researchers have developed a molecule that allows an important ion channel to be regulated -- a breakthrough with therapeutic potential. Located in the cell membrane, TRPM8 ion channels are ...

In this important manuscript, the authors provide evidence for this mechanism in two different mechanically gated channels. The experiments were carried out in the same membranes, but the evidence is ...

In the cell membrane, TRPM8 acts as a receptor for cold, enabling humans to sense cold. Researchers at ...

When transport processes in cells do not function properly, this often results in diseases such as metabolic disorders, high blood pressure, kidney and lung damage or inflammation. In the ...

Neurons are cells that act as the ... Additionally, the authors identified two ion channels that are essential for the change of membrane voltages triggered by sensory stimulation.