The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...

Dan G. Duda, DMD, Ph.D., of the Edwin L. Steele Laboratories for Tumor Biology and Department of Radiation Oncology at ...

Exicure, Inc. (Nasdaq: XCUR, “Exicure”, “the Company”), has announced the signing of a Memorandum of Understanding (MOU) with ...

Both approaches led to fewer granulomas forming compared to controls. "We found that CXCR4 signaling is crucial to the ...

Notably, the interaction between CXCR4 and the beta-2 adrenergic receptor (B2AR) presents an alternative signaling pathway that is synergistically dependent on the activation of both CXCR4 and B2AR.