The NTase domain binds to the broken DNA strands at and flanking the nick, the OB domain contacts the continuous template strand surrounding the nick, and the HhH domain binds both strands across the ...

These astonishing results indicate that DNA that was completely broken down can revert back ... et al. Double-strand breaks associated with repetitive DNA can reshape the genome.

DNA can last for many centuries. A new DNA storage technology works in the laboratory with parallelizable writing processes ...

"How cells prevent separation of broken DNA ends has been somewhat of ... "Individual PARP1 molecules detect the ...

Such damage can lead to breaks in the DNA strand. If DNA damage is not properly ... to "repair cafés," where people gather to fix broken items. “Such a central place makes the process more ...

A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, ...

Researchers have mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...