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EurekAlert!
4 年
PD-1/PD-L1抑制剂治疗肺癌的前景与挑战
PD-1有两个结合配体,PD-L1(B7-H1或CD274)和PDL2(B7-DC或CD273)。PD-L1表达于活化的T细胞、B细胞、巨噬细胞、树突状细胞和癌细胞,PD-L2的表达有限,主要表达 ...
BioWorld
1 个月
Duality Biologics reports preclinical findings with B7-H3/PD-L1-targeting ADC
Duality Biologics Ltd. presented preclinical data on DB-1419, a potentially first-in-class bispecific antibody-drug conjugate (ADC) consisting of a humanized antibody targeting B7-H3 and PD-L1 ...
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