Transfecting LCMV-GP into a fibrosarcoma line as a surrogate tumor antigen, dendritic-cell vaccination against GP led to an anti-tumor immune response as well as diabetes in RIP-GP mice as ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

The immune system has evolved to mount immune responses against foreign pathogens and to remain silent against self-antigens ... or autoimmunity. Dendritic cells (DCs) actively participate ...

particularly antigen-presenting cells (APCs) such as dendritic cells—the main T cell activators. The process begins when cancer cells release protein fragments, or antigens, that are captured by ...