Abiraterone acetate (CB7630), a pregnenolone analog, is an orally administered small molecule that irreversibly inhibits a rate-limiting enzyme in androgen biosysnthesis, CYP17, and blocks the ...

This Prostate Cancer Awareness Month, we’re celebrating over 10 years since abiraterone was first recommended by NICE in England as a treatment for advanced prostate cancer. We share the story of the ...

But it remains to be seen how long this can continue because of dwindling sales of its inflammatory disease drug Remicade and a looming threat to Zytiga. Zytiga (abiraterone), approved since 2011 ...

Future Oncol. 2010;6(5):665-679. Three Phase I studies by O'Donnell and colleagues have reported the pharmacodynamic activity of abiraterone acetate, which was originally developed as an oral ...

Although not a cure, abiraterone can help stop prostate cancer spreading to other parts of the body. NHS England said it would review the drug's use for more men next year. In England and Northern ...

The Institute of Cancer Research, London, has sold a portion of its royalty entitlement for the prostate cancer drug abiraterone for an undisclosed sum. The sale, to Drug Royalty III, a private equity ...

In the trial, doctors compared olaparib with two other commonly prescribed prostate drugs (hormone treatments called abiraterone and enzalutamide). It appeared to delay cancer growth by months ...

The drug's safety and efficacy were evaluated in combination with abiraterone and ADT against abiraterone and ADT alongside placebo. The Truqap combination showed a promising early trend towards ...

The phase 3 CAPItello-281 trial has been comparing the efficacy and safety of the drug in combination with abiraterone and androgen deprivation therapy (ADT) against abiraterone and ADT plus placebo ...

Gozetotide is a drug for diagnostic application in adults with prostate cancer. It is currently the only diagnostic agent that recognizes PSMA-positive prostate cancer and can therefore identify ...

AstraZeneca (NASDAQ:AZN) reported positive results from a Phase 3 study of its drug Truqap in the treatment ... showed that Truqap in combination with abiraterone and androgen deprivation therapy ...