45mg once every 6 months (24 weeks ... Mean plasma concentration (Lupron Depot 7.5mg): 20 ng/mL at 4 hours and 0.36 ng/mL at 4 weeks; (Lupron Depot 22.5mg): 48 ng/mL at 4 hours and 0.67 ng ...

22.5mg once every 3 months (12 weeks ... Depot 30mg): 59.3 ng/mL at 4 hours and 0.30 ng/mL at 16 weeks; (Lupron Depot 45mg): 6.7 ng/mL at 2 hours and 0.07 ng/mL at 24 weeks.